Myosin light chain kinase in microvascular endothelial barrier function
نویسندگان
چکیده
منابع مشابه
Abl Tyrosine Kinase Phosphorylates Nonmuscle Myosin Light Chain Kinase to Regulate Endothelial Barrier Function
Nonmuscle myosin light chain kinase (nmMLCK), a multi-functional cytoskeletal protein critical to vascular homeostasis, is highly regulated by tyrosine phosphorylation. We identified multiple novel c-Abl-mediated nmMLCK phosphorylation sites by mass spectroscopy analysis (including Y231, Y464, Y556, Y846) and examined their influence on nmMLCK function and human lung endothelial cell (EC) barri...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2010
ISSN: 0008-6363
DOI: 10.1093/cvr/cvq144